業績

2018

Komori T, Ono M, Hara ES, Ueda J, Nguyen HTT, Nguyen HT, Yonezawa T, Maeba T, Kimura-Ono A, Takarada T, Momota R, Maekawa K, Kuboki T, Oohashi T. Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium. Sci Rep. 8:2612 (2018)

Asano K, Edamatsu M, Hatipoglu O F, Cilek M Z, Inagaki J, Ohtsuki T, Oohashi T, Hirohata S. Host-produced ADAMTS4 inhibited early stage of tumor growth. Acta Med Okayama, in press

Cicanic M, Edamatsu M, Bekku Y, Vorisek I, Oohashi T, Vargova L. A deficiency of the link protein Bral2 affects the size of the extracellular space in the thalamus of aged mice. J Neurosci Res. 96(2):313-327 (2018)

Ishikawa T, Nishida T, Ono M, Takarada T, Nguyen HT, Kurihara S, Furumatsu T, Murase Y, Takigawa M, Oohashi T, Kamioka H, Kubota S. Physiological role of urothelial cancer-associated one long noncoding RNA in human skeletogenic cell differentiation. J Cell Physiol. 233(6):4825-4840 (2018)

Ono M, Masaki A, Maeda A, Kilts TM, Hara ES, Komori T, Pham H, Kuboki T, Young MF. CCN4/WISP1 controls cutaneous wound healing by modulating proliferation, migration and ECM expression in dermal fibroblasts via α5β1 and TNFα. Matrix Biol. 17: 30400-6 (2018)

Yoshihara-Hirata C, Yamashiro K, Yamamoto T, Aoyagi H, Ideguchi H, Kawamura M, Suzuki R, Ono M, Wake H, Nishibori M, Takashiba S. Anti-HMGB1 neutralizing antibody attenuates periodontal inflammation and bone resorption in a murine periodontitis model. Infect Immun. Mar 12. pii: IAI.00111-18 (2018)

Morisawa A, Okui T, Shimo T, Ibaragi S, Okusha Y, Ono M, Nguyen TTH, Hassan NMM, Sasaki A. Ammonium tetrathiomolybdate enhances the antitumor effects of cetuximab via the suppression of osteoclastogenesis in head and neck squamous carcinoma. Int J Oncol. 52(3):989-999 (2018)

2017

Asano K, Nelson CM, Nandadasa S, Aramaki-Hattori N, Lindner DJ, Alban T, Inagaki J, Ohtsuki T, Oohashi T, Apte SS, Hirohata S. Stromal Versican Regulates Tumor Growth by Promoting Angiogenesis. Sci Rep. 7:17225 (2017)

Ono M, Oshima M, Ogawa M, Sonoyama W, Hara ES, Oida Y, Shinkawa S, Nakajima R, Mine A, Hayano S, Fukumoto S, Kasugai S, Yamaguchi A, Tsuji T, Kuboki T. Practical whole-tooth restoration utilizing autologous bioengineered tooth germ transplantation in a postnatal canine model. Sci Rep. 7:44522 (2017)

Popelář J, Díaz Gómez M, Lindovský J, Rybalko N, Burianová J, Oohashi T, Syka J. The absence of brain-specific link protein Bral2 in perineuronal nets hampers auditory temporal resolution and neural adaptation in mice. Physiol Res. 66(5):867-880 (2017)

Sado Y, Inoue S, Tomono Y, Matsuyama M, Fukushima M, Oohashi T, Jogahara T, Oda S. Monoclonal Suncus Antibodies: Generation of Fusion Partners to Produce Suncus-Suncus Hybridomas. Acta Histochem. Cytochem. 50(2):71-84 (2017)

Matoba R, Morizane Y, Shiode Y, Hirano M, Doi S, Toshima S, Araki R, Hosogi M, Yonezawa T, Shiraga F. Suppressive effect of AMP-activated protein kinase on the epithelial-mesenchymal transition in retinal pigment epithelial cells. PLoS One. 12(7):e0181481 (2017)

Shiode Y, Morizane Y, Matoba R, Hirano M, Doi S, Toshima S, Araki R, Hosogi M, Takahashi K, Kanzaki Y, Yonezawa T, Shiraga F. A novel cell exclusion zone assay with a barrier made from room temperature vulcanizing silicone rubber. PLoS One. 12(12):e0190198 (2017)

Shiode Y, Morizane Y, Matoba R, Hirano M, Doi S, Toshima S, Takahashi K, Araki R, Kanzaki Y, Hosogi M, Yonezawa T, Yoshida A, Shiraga F. Invest Ophthalmol Vis Sci. 58(11):4847-4855 (2017)

2016

Murata T, Katayama K, Oohashi T, Jahnukainen T, Yonezawa T, Sado Y, Ishikawa E, Nomura S, Tryggvason K, Ito M. COL4A6 is dispensable for autosomal recessive Alport syndrome. Sci Rep. 6:29450 (2016)

Hara E, Ono M, Yoshioka Y, Ueda J, Hazehara Y, Pham H, Matsumoto T, Kuboki T. Antagonistic effects of insulin and TGF-ß3 during chondrogenic differentiation of human BMSCs under minimal amount of factors. Cells Tissues Organs. 201(2): 88-96 (2016)

Faralli A, Dagna F, Albera A, Bekku Y, Oohashi T, Albera R, Rossi F, Carulli D.
Modifications of perineuronal nets and remodelling of excitatory and inhibitory afferents during vestibular compensation in the adult mouse.
Brain Structure and Function. 221(6):3193-209 (2016)

Kimura K, Nakayama M, Naito I, Komiyama T, Ichimura K, Asano H, Tsukuda K, Ohtsuka A, Oohashi T, Miyoshi S, Ninomiya Y.
Human collagen XV is a prominent histopathological component of sinusoidal capillarization with the hepatocellular carcinogenesis.
Int J Clin Oncol.21(2):302-9 (2016)

2015

Oohashi T, Edamatsu M, Bekku Y, Carulli D.
The hyaluronan and proteoglycan link proteins: Organizers of the brain extracellular matrix and key molecules for neuronal function and plasticity. Exp Neurol. 274 (Pt B), 134-144 (2015) doi: 10.1016/j.expneurol.2015.09.010.

Yoshioka Y, Ono M, Maeda A, Kilts TM, Hara ES, Khattab H, Ueda J, Aoyama E, Oohashi T, Takigawa M, Young MF, and Kuboki T. CCN4/WISP-1 positively regulates chondrogenesis by controlling TGF-b3 function. Bone, 83, 162-170 (2015)

大橋俊孝 ことば「ランビエ絞輪とパラノード」「跳躍伝導」,生化学, 87巻5号,643. (2015)

大橋俊孝枝松緑別宮洋子 成熟脳のペリニューロナルECMの形成と機能について,生化学, 87巻3号,393-396 (2015)

大橋俊孝, 基底膜ツールキットとしての XV/XVIII型コラーゲン遺伝子の機能,岡山医学会雑誌, 第127巻,103-109 (2015)

Ishii H, Kamikawa S, Hirohata S, Mizutani A, Abe K, Seno M, Oohashi T, Ninomiya Y.
Eosinophil cationic protein shows survival effect on H9c2 cardiac myoblast cells with enhanced phosphorylation of ERK and Akt/GSK3β under oxidative stress.
Acta Med Okayama. 69(3):145-153 (2015)

Kawata K, Morishita K, Nakayama M, Yamada S, Kobayashi T, Furusawa Y, Arimoto-Kobayashi S, Oohashi T, Makishima M, Naitou H, Ishitsubo E, Tokiwa H, Tai A, Kakuta H.
RXR partial agonist produced by side chain repositioning of alkoxy RXR full agonist retains antitype 2 diabetes activity without the adverse effects.
J Med Chem. 58(2): 912-926 (2015)

Maeda A, Ono M,  Holmbeck K, Li L, Kilts TM, Kram V, Noonan ML, Yoshioka Y, McNerny E, Tantillo M, Kohn D, Lyons KM, Robey PG, Young MF. WNT1 induced secreted protein-1 (WISP1): A novel regulator of bone turnover and Wnt signaling. Journal of Biological Chemistry, 290(22):14004-18 (2015)

Hara ES, Ono M, Pham HT, Sonoyama W, Kubota S, Takigawa M, Matsumoto T, Young MF, Olsen BR, Kuboki T. Fluocinolone Acetonide is a Potent Synergistic Factor of TGF-β3-Associated Chondrogenesis of Bone Marrow-Derived Mesenchymal Stem Cells for Articular Surface Regeneration. J Bone Miner Res. 30(9), 1585-96 (2015).

Ishimoto K, Hayano S, Yanagita T, Kurosaka H, Kawanabe N, Itoh S, Ono M, Kuboki T, Kamioka H, Yamashiro T. Topical application of lithium chloride on the pulp induces dentin regeneration. PLoS One. 26;10(3):e0121938 (2015).

2014

Maehara A, Nishida K, Furutani M, Matsumoto E, Ohtsuka A, Ninomiya Y, Oohashi T.
Light and electron microscopic detection of inflammation-targeting liposomes encapsulating high-density colloidal gold in arthritic mice.
Inflamm Res. 63(2):139-147 (2014)

Demircan K, Topcu V, Takigawa T, Akyol S, Yonezawa T, Ozturk G, Ugurcu V, Hasgul R, Yigitoglu MR, Akyol O, McCulloch DR, Hirohata S.
ADAMTS4 and ADAMTS5 knockout mice are protected from versican but not aggrecan or brevican proteolysis during spinal cord injury.
Biomed Res Int. 2014:693746 (2014)

Inagaki J, Takahashi K, Ogawa H, Asano K, Faruk Hatipoglu O, Cilek MZ, Obika M, Ohtsuki T, Hofmann M, Kusachi S, Ninomiya Y, Hirohata S.
ADAMTS1 inhibits lymphangiogenesis by attenuating phosphorylation of the lymphatic endothelial cell-specific VEGF receptor.
Exp Cell Res. 323(2):263-275 (2014)

Miyoshi T, Nakamura K, Yoshida M, Miura D, Oe H, Akagi S, Sugiyama H, Akazawa K, Yonezawa T, Wada J, Ito H.
Effect of vildagliptin, a dipeptidyl peptidase 4 inhibitor, on cardiac hypertrophy induced by chronic beta-adrenergic stimulation in rats.
Cardiovasc Diabetol. 3:43 (2014)

Abali O, Gokce EC, Cemil B, Erdogan B, Yonezawa T, Demircan K.
Early Induction of ADAMTS 1, -4, -5 and -9 in IL-Stimulated Mouse Astrocytes.
Turk Neurosurg. 24(4):519-24 (2014)

Mukai T, Ishida S, Ishikawa R, Yoshitaka T, Kittaka M, Gallant R, Lin YL, Rottapel R, Brotto M, Reichenberger EJ, Ueki Y.
SH3BP2 cherubism mutation potentiates TNF-α-induced osteoclastogenesis via NFATc1 and TNF-α-mediated inflammatory bone loss.
J Bone Miner Res. 2014 Dec;29(12):2618-35 (2014)

Yoshitaka T, Mukai T, Kittaka M, Alford LM, Masrani S, Ishida S, Yamaguchi K, Yamada M, Mizuno N, Olsen BR, Reichenberger EJ, Ueki Y.
Enhanced TLR-MYD88 signaling stimulates autoinflammation in SH3BP2 cherubism mice and defines the etiology of cherubism.
Cell Rep. 8(6):1752-166 (2014)

〜2013 まで(抜粋)

Susuki K, Chang KJ, Zollinger DR, Liu Y, Ogawa Y, Eshed-Eisenbach Y, Dours-Zimmermann MT, Oses-Prieto JA, Burlingame AL, Seidenbecher CI, Zimmermann DR, Oohashi T, Peles E, Rasband MN.
Three mechanisms assemble central nervous system nodes of Ranvier.
Neuron. 78(3):469-82 (2013)

Young TR, Bourke M, Zhou X, Oohashi T, Sawatari A, Fässler R, Leamey CA.
Ten-m2 is required for the generation of binocular visual circuits.
J Neurosci. 33(30):12490-12509 (2013)

Demircan K, Yonezawa T, Takigawa T, Topcu V, Erdogan S, Ucar F, Armutcu F, Yigitoglu MR, Ninomiya Y, Hirohata S.
ADAMTS1, ADAMTS5, ADAMTS9 and aggrecanase-generated proteoglycan fragments are induced following spinal cord injury in mouse.
Neurosci Lett. 544: 25-30 (2013)

Momota R, Narasaki M, Komiyama T, Naito I, Ninomiya Y, Ohtsuka A.
Drosophila type XV/XVIII collagen mutants manifest integrin mediated mitochondrial dysfunction, which is improved by cyclosporin A and losartan.
Int J Biochem Cell Biol. 45(5):1003-1011 (2013)

Bekku Y, Saito M, Moser M, Fuchigami M, Maehara A, Nakayama M, Kusachi S, Ninomiya Y, Oohashi T. Bral2 is indispensable for the proper localization of brevican and the structural integrity of the perineuronal net in the brainstem and cerebellum.
J Comp Neurol. 520(8):1721-36 (2012)

Obika M, Ogawa H, Takahashi K, Li J, Hatipoglu OF, Cilek MZ, Miyoshi T, Inagaki J, Ohtsuki T, Kusachi S, Ninomiya Y, Hirohata S.
Tumor growth inhibitory effect of ADAMTS1 is accompanied by the inhibition of tumor angiogenesis.
Cancer Sci. 103(10):1889-1897 (2012)

Bekku Y, Vargová L, Goto Y, Vorísek I, Dmytrenko L, Narasaki M, Ohtsuka A, Fässler R, Ninomiya Y, Syková E, Oohashi T. Bral1: its role in diffusion barrier formation and conduction velocity in the CNS.
J Neurosci. 30(8):3113-3123 (2010)

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